Today, we will tell you about the relationship between the phobia in general and agoraphobia in particular in relation with the brain.

There are several areas of the brain that are affected in phobia. This is when the activation of the amygdala causes anticipatory anxiety or avoidance (conditioned fear) while activation of the hypothalamus activates the sympathetic nervous system.

Other regions of the brain involved in phobia include the thalamus and the cortical structures, which may form a key neural network along with the amygdala. Stimulation of the locus coeruleus increases noradrenaline release mediating physiological and behavioural arousal.

There are studies conducted using imaging techniques, particularly magnetic resonance imaging (MRI), have helped to identify different areas of the brain associated with anxiety responses.

In particular, research has focused on changes in the amygdala, which is sometimes referred to as the “fear center”. This part of the brain regulates fear, memory, and emotion besides coordinating these resources with heart rate, blood pressure and other physical responses to stressful events. Some evidence suggests that the amygdala in people with anxiety disorders is highly sensitive to novel or unfamiliar situations and reacts with a high stress response.

Thus in other words, amygdala is part of the brain that highly influence in phobia compare to the other part of the brain.



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